Registration Dossier
Registration Dossier
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EC number: 418-570-8 | CAS number: 25383-07-7
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 4.6 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 46 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.46 µg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.018 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.002 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.904 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 33.3 mg/kg food
- Assessment factor:
- 30
Additional information
The following values are available from the ecotoxicity section:
LC50 96h Danio rerio: > 100 mg/L
NOEC 96h Danio rerio: > 100 mg/L
EC50 48h Daphnia magna: 86 mg/L
NOEC 48h Daphnia magna: 59 mg/L
EC50 72h Pseudokirchnerella subcapitata: 4.6 mg/L (biomass)
EC50 72h Pseudokirchnerella subcapitata: 17.7 mg/L (biomass)
NOEC 72h Pseudokirchnerella subcapitata: < 1 mg/L (biomass)
NOEC 72h Pseudokirchnerella subcapitata: < 1mg/L (biomass)
NOEC 3h activated sludges = 100 mg/L
EC10 3h activated sludges = 90 mg/L (95% Confidence interval 63 – 120 mg/L)
EC50 3h activated sludges = 6200 mg/L extrapolated (95 % Confidence interval 4000 – 9900 mg/L)
PNECs were derived according to ECHA REACH guidance (R.10).
Conclusion on classification
According to Regulation (EC) n- 1272/2008, Phenethylammonium salt of fosfomycin is classified for its environmental hazard as Aquatic Chronic 2, H411.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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