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EC number: 247-501-2 | CAS number: 26175-68-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2006
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: well performed OECD study according GLP. The N-monomethyl-amide was tested and the results are used as read across for the claimed N,N-dimethyl-amide
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- 85776-36-9
- EC Number:
- 617-758-9
- Cas Number:
- 85776-36-9
- IUPAC Name:
- 85776-36-9
- Details on test material:
- purity: ca. 96%
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Aerobic activated sludge from waste water treatment plant (ARA Ergolz II, Füllinsdorf, Switzerland) predominantly domestic wastewater.
The sludge was washed twice with tap water - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 7
- Sampling time:
- 1 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 18
- Sampling time:
- 7 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 23
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 25
- Sampling time:
- 18 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 29
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other:
- Conclusions:
- The Monomethyl sulfonamid ADCSMF (CAS 85776-36-9; Benzenesulfonamide, 4-amino-2,5-dichloro-N-methyl-) was not readily biodegradable.
Therefore, it is expected that the dimethy sulfonamide, that is subject for the registrations is also not readily biodegradable. - Executive summary:
The test item ADCSMF (CAS 85776 -36 -9; Benzenesulfonamide, 4-amino-2,5-dichloro-N-methyl-) was investigated in a manometric respirometry test over 28 days according to OECD 301F. ADCSMF was not readily biodegradable under the test conditions within 28 days. It is expected that the dimethy sulfonamide, that is subject for the registrations is also not readily biodegradable.
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