Registration Dossier
Registration Dossier
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EC number: 270-984-6 | CAS number: 68512-62-9 A complex residuum from the vacuum distillation of the residuum from the atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly greater than C13 and boiling above approximately 230°C (446°F).
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: RELIABLE SUMMARY REPORT
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- IUCLID DATASET SUBSTANCE ID:68512-62-9
- Author:
- EUROPEAN COMMISSION - EUROPEAN CHEMICALS BUREAU
- Year:
- 2 000
- Bibliographic source:
- IUCLID DATASET SUBSTANCE ID:68512-62-9 PG 25-26
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Test type:
- acute toxic class method
Test material
- Reference substance name:
- Fuel oil, no. 6
- EC Number:
- 271-384-7
- EC Name:
- Fuel oil, no. 6
- Cas Number:
- 68553-00-4
- IUPAC Name:
- 68553-00-4
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- not specified
- Doses:
- 3.5, 6.5, 7.5, 10 and 25 ml/kg
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- ca. 5 500 mg/kg bw
- Based on:
- test mat.
Any other information on results incl. tables
Complete mortality was found at the two highest doses and 10% mortality at the lowest dose. Animals that died were found to have congested livers and intestinal irritation. Surviving rats were found at necropsy to have slightly congested livers and kidneys.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
