Registration Dossier
Registration Dossier
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EC number: 200-526-2 | CAS number: 62-23-7
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- genetic toxicity in vitro
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- Zeiger E et al
- Year:
- 1 987
- Bibliographic source:
- Environ Mutagen 9 (3): 269-80
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- there is no guideline available
- GLP compliance:
- not specified
- Type of assay:
- in vitro mammalian chromosome aberration test
Test material
- Reference substance name:
- 4-nitrobenzoic acid
- EC Number:
- 200-526-2
- EC Name:
- 4-nitrobenzoic acid
- Cas Number:
- 62-23-7
- Molecular formula:
- C7H5NO4
- IUPAC Name:
- 4-nitrobenzoic acid
Constituent 1
Results and discussion
Test results
- Species / strain:
- Chinese hamster Ovary (CHO)
Any other information on results incl. tables
4-nitrobenzoic acid (NBA) was for mutagenicity in Salmonella and for its ability to induce chromosome aberrations and sister chromatid exchanges (SCE) in cultured Chinese hamster ovary (CHO) cells. NBA was positive in Salmonella and CHO cells.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
