Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

Currently viewing:

Administrative data

Endpoint:
skin sensitisation: in vivo (non-LLNA)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: study according to guideline

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
Gad, S.C. et al.
Year:
1986
Bibliographic source:
Gad, S.C. et al. 1986. Toxicol Appl Pharmacol 84: 93-114. cited in: IUCLID (1995) data sheet for n-butyl acetate.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: according to Magnusson and Kligman, 1969.
GLP compliance:
not specified
Type of study:
guinea pig maximisation test

Test material

Constituent 1
Chemical structure
Reference substance name:
N-butyl acetate
EC Number:
204-658-1
EC Name:
N-butyl acetate
Cas Number:
123-86-4
Molecular formula:
C6H12O2
IUPAC Name:
butyl acetate

In vivo test system

Test animals

Species:
guinea pig
Strain:
Hartley
Sex:
not specified

Results and discussion

Any other information on results incl. tables

not sensitizing

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
not sensitizing