Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001
Report date:
2001

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
Deviations:
no

Test material

Test animals

Species:
rabbit
Strain:
New Zealand White

Test system

Type of coverage:
semiocclusive

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
erythema score
Basis:
animal #1
Time point:
other:
Score:
2
Irritation parameter:
erythema score
Basis:
animal #2
Time point:
other:
Score:
2
Irritation parameter:
erythema score
Basis:
animal #3
Time point:
other:
Score:
1.3
Irritation parameter:
erythema score
Basis:
mean
Time point:
other:
Score:
ca. 2
Max. score:
2
Reversibility:
fully reversible within:
Remarks on result:
other:
Irritation parameter:
edema score
Basis:
animal #1
Time point:
other:
Score:
2
Irritation parameter:
edema score
Basis:
animal #2
Time point:
other:
Score:
1
Irritation parameter:
edema score
Basis:
animal #3
Time point:
other:
Score:
0.67
Irritation parameter:
edema score
Basis:
mean
Time point:
other:
Score:
ca. 2
Max. score:
2
Reversibility:
fully reversible within:
Remarks on result:
other:

Applicant's summary and conclusion