Registration Dossier
Registration Dossier
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EC number: 700-184-9 | CAS number: 1000172-11-1
Endpoint summary
Administrative data
Description of key information
Oral LD0 in four surrogate substances (all decene oligomers) all >5000mg/kg
Dermal LD0 in a surrogate substance >2000mg/l
Key value for chemical safety assessment
Additional information
There is no oral acute toxicity data available on the substance. However, acute oral toxicity limit tests are available on a number of closely related substances: four hydrogenated decene polyalphaolefin oligomers ranging from the dimer to a mixture of predominantly the tetramer and pentamer, representing a number average molecular weight range of 289 to 623. (The molecular weight of the substance polyalphaolefin oligomer is 448 and is branched compared to the linear structure of the surrogates.) The LD50 (and in fact the LD0's) of all the surrogates are >5000mg/kg. Due to the similar nature of the surrogates to the test substance, it can be extrapolated with some confidence that the acute oral toxicity of "Pentadecane, 7-methylene mixed with 1-tetradecene, dimers and trimers, hydrogenated" (LD0 and LD50 will also be >5000mg/kg.
There is no inhalation acute toxicity data available on the substance.
There is no dermal acute toxicity data available on the substance. An acute dermal toxicity test was conducted with rats to determine the potential for a C24 -C56 hydrogenated polyalphaolefin to produce toxicity from a single topical application. Under the conditions of this study, the single dose acute dermal LD50 of the test substance is greater than 2000 mg/kg body weight in male and female rats. The study was conducted according to current OECD and EPA guidelines and is compliant with GLP standards. Based on the fact that dermal absorption is negligible (see chapter 7.1.2) it can be assumed that the dermal LD50 will be greater than the oral LD50 of 5000mg/kg.
Justification for classification or non-classification
Oral LD0>5000mg/kg. No classification required.
Based on the results of the available acute dermal toxicity data, this substance would not be classified for acute dermal toxicity in accordance with the current EU guidelines and the EU GHS classification regulation.
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