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Diss Factsheets

Physical & Chemical properties

Vapour pressure

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Administrative data

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Referenceopen allclose all

Endpoint:
vapour pressure
Type of information:
other: bibliography
Adequacy of study:
weight of evidence
Study period:
1989
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Calendula officinalis hydroglycerinated extract is a UVCB and natural complex substance, and is assessed through constituents approach taking into account one of the main constituent : glycerol present at 50%.
Qualifier:
according to guideline
Guideline:
other: the guideline is not described on the document
Key result
Test no.:
#1
Temp.:
ca. 25 °C
Vapour pressure:
ca. 0 hPa
Key result
Vapour pressure:
ca. 0.003 hPa
Conclusions:
The vapor pressure of glycerol is 0.000106 hPa (calculated) at 25 deg C (=1.06E-5 kPa) and 0.0033 hPa (measured) (source : EFSA)
The vapor pressure of glycerol is 1.68x10-4 mm Hg at 25 deg C (source : Aubert, T.E., R.P. Danner. Physical and Thermodynamic Properties of Pure Chemicals Data Compilation. Washington, D.C.: Taylor and Francis, 1989.] **PEER REVIEWED** )

Endpoint:
vapour pressure
Type of information:
other: bibliography
Adequacy of study:
weight of evidence
Study period:
2014
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Calendula officinalis hydroglycerinated extract is a UVCB and natural complex substance, and is assessed through constituents approach taking into account one of the main constituent : water present at 50%.
Qualifier:
according to guideline
Guideline:
other: the guideline is not described on the document
Key result
Test no.:
#1
Temp.:
ca. 25 °C
Vapour pressure:
ca. 3.169 kPa
Remarks on result:
other: source HSDB
Key result
Test no.:
#2
Temp.:
ca. 100 °C
Vapour pressure:
ca. 760 mm Hg
Remarks on result:
other: source HSDB ([Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. V3: 3692] **PEER REVIEWED**
Key result
Test no.:
#3
Temp.:
ca. 0 °C
Vapour pressure:
ca. 611.657 Pa
Remarks on result:
other: source HSDB ([Haynes, W.M. (ed.). CRC Handbook of Chemistry and Physics. 94th Edition. CRC Press LLC, Boca Raton: FL 2013-2014, p. 6-13] **PEER REVIEWED** )
Conclusions:
The vapour pressure of water is 3.169 kPa at 25°C.

Description of key information

According to data available, vapour pressure of the 2 main constituents reprensenting 98.5% of the Calendula officinalis hydroglycerinated extract is as following :

- water, VP           ca 3,169 kPa (at 25°C)

- glycerol, VP       ca 1.06E-5 kPa (at 25 °C)

Key value for chemical safety assessment

Additional information

The vapor pressure of the test substance was estimated using a constituents approach.

This final extract is a natural complex substance. It is a mixture of several components, and two of them represent about 98.5% of the mixture.

On the basis of available data, the vapour pressure of the calendula extract is estimated between 1.06E-5 and 3.169 kPa at 25°C.