Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed

Additional information

CALCIUM DIFLUORIDE is of low acute toxicity by the oral, inhalation and intraperitoneal routes and low acute dermal toxicity can be reliably predicted. No classification is proposed for acute toxicity according to the CLP regulation (1272/2008/EC).


SODIUM CHLORIDE is not formally classified in the EU (according to Regulation EC No. 1272/2008 Annex VI, Table 3.1 and Regulation EC No. 1272/2008 Annex VI, Table 3.2).


For POTASSIUM CHLORIDE, based on the available data no classification has to be required.


For TRISODIUM HEXAFLUOROALUMINATE,  in accordance to Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008, classification is not necessary for acute oral and dermal toxicity based on the available data.


After inhalation of cryolite an acute LC50 of 4.47 mg/L was estimated in rats (4 hours exposure). Therefore, classification as harmful (Xn); R20 is appropriate in accordance to Directive 67/548/EEC. Under EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008, classification with H332 (Cat. 4) is applicable.


Because in RAL 3.0 the cryolite is present in a concentration below 1%, the product is not harmful.

Justification for classification or non-classification

The only hazardous component of RAL 3.0 is trisodium hexafluoroaluminate. It is present in amounts less than 1%. Because of this the preparation is not harmful.


No adverse health effects have been reported in RAL 3.0 product preparation workers or in those using this product.