Registration Dossier
Registration Dossier
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EC number: 204-635-6 | CAS number: 123-56-8
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
Two aquatic studies are available covering two trophic levels:
Aquatic invertebrate (Aschacher 2002):
In a test conducted according to ÖNORM EN ISO 6314, Daphnia magna were exposed to succinimide to concentrations of 10, 11, 12, 13, 14, and 15 g succinimide/L (nominal values) for 24 h. The effects caused by these concentrations did not follow a dose response and an EC50 could not be identified in the test. The range finder showed that no immobilisation occurred when D. magna were exposed up to 5 g/L. Therefore, it is concluded that the 24-h EC50 (D. magna, immobilisation) is above 5 g/L and below 10 g/L.
Aquatic algae (Seeland-Fremer 2019):
In a growth inhibition study conducted according to OECD guideline 201 and GLP the freshwater algae Pseudokirchneriella subcapitata was exposed to 962, 293, 83.7, 25.8 and 6.18 mg succinimide/L (geometric mean of measured concentration) for 72 h. No significant effect was seen for the endpoint growth rate up to the highest concentration tested. The endpoint yield revealed a significant effect at 962 mg/L with 11 % inhibition.
72-h NOErC ≥ 960 mg test item/L
72-h LOErC > 960 mg test item/L
72-h NOEyC = 293 mg test item/L
72-h LOEyC = 960 mg test item/L
In an inherent biodegradability test according to EN ISO 9888 (Schoisswohl 2001) the test item degraded to 99 % within 4 days. Hence, the substance is considered to be inherently biodegradable.
Taking into account these results, the substance does not have to be classified as aquatic toxic according to the CLP Regulation (Regulation (EC) No 1272/2008).
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