Registration Dossier
Registration Dossier
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EC number: 290-505-4 | CAS number: 90170-70-0
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- March 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The deviation of the temperature during the test was higher than ±0.5 °C. The highest deviation was 2.4 °C. This deviation does not have any effect on the overall study conclusions.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The deviation of the temperature during the test was higher than ±0.5 °C. The highest deviation was 2.4 °C. This deviation does not have any effect on the overall study conclusions.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Key result
- Water solubility:
- < 0.2 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- > 7.79 - < 8.51
- Conclusions:
- The water solubility of Solvent Blue 79B was determined to be less than the quantitation limit (0.2 mg/L after dilution) using the column elution method and HPLC for analysis.
- Executive summary:
The Column Elution method, according to OECD 105 was used to evaluate the water solubility of Solvent Blue 79B. HPLC was used as the method for analysis. Solvent Blue 79B was not detected in any of the analysed solutions, therefore the water solubility can be concluded to be less than the LOQ of the method (0.2mg/L)
Reference
Results of the determination of Solvent Blue 79B concentrations
Analytical occasion / Time Period |
Flow rate |
Measured concentration ofSolvent Blue 79B(mg/L) |
||
20 March 2018 / 21 hours |
~ 12.5 |
not detected |
pH=8.15 |
|
21 March 2018 / 45 hours |
not detected |
pH=8.00 |
||
22 March 2018 / 69 hours |
not detected |
pH=8.38 |
||
23 March 2018 / 93 hours |
not detected |
pH=8.51 |
||
26 March 2018 / 163 hours |
not detected |
pH =8.38 |
||
Mean |
|
not detected |
||
20 March 2018 / 21 hours |
~ 25 |
not detected |
pH=7.87 |
|
21 March 2018 / 45 hours |
not detected |
pH=7.79 |
||
22 March 2018 / 69 hours |
not detected |
pH=8.18 |
||
23 March 2018 / 93 hours |
not detected |
pH=8.26 |
||
26 March 2018 / 163 hours |
not detected |
pH=8.12 |
||
Mean |
|
not detected |
||
Mean of the two test |
|
|
not detected |
|
Description of key information
The water solubility of Solvent Blue 79B was determined using the column elution method. No Solvent Blue 79 B could be detected in any of the test solutions therefore the solubility was determined to be less than the quantitation limit (0.2 mg/L after dilution) at 20 °C ± 0.5 °C.
Key value for chemical safety assessment
- Water solubility:
- 0.2 mg/L
- at the temperature of:
- 20 °C
Additional information
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