Trimethyl orthoacetate

Guidance on Safe Use

First-aid measures

4.1. Description of first aid measures

General information:

Remove/Take off immediately all contaminated clothing. Pay attention to self-protection.

In case of unwellness, call a physician. Show this safety data sheet to the physician.

After inhalation:

Remove affected person to fresh air. In case of unwellness, seek medical advice.

After skin contact:

Immediately wash with water and soap and rinse thoroughly.

If irritation persists or rash occurs, consult a physician.

After eye contact:

Rinse opened eye for several minutes under running water. In irritation persists, consult an ophthalmologist.

After swallowing:

Thoroughly rinse mouth with water and immediately call a physician or poison centre.

Do not induce vomiting.

If unconscious place in recovery position and call a physician immediately.

Never give anything by mouth to an unconscious person.

4.2. Most important symptoms and effects, both acute and delayed

Skin contact: Allergic reactions, irritating effects.

After swallowing: Hydrolysis leads to formation of methanol.

Symptoms: vertigo, nausea, headache, convulsions, sight disorder,

acidosis.

4.3. Indication of any immediate medical attention and special treatment needed

Treat symptomatically (decontamination, vital functions).

Notes for the doctor: treatment of methanol poisoning may require use of ethanol.

Fire-fighting measures

5.1. Extinguishing media

Suitable extinguishing media: Water spray, alcohol resistant foam, dry powder, carbon dioxide (CO2).

Fight larger fires with water spray or alcohol-resistant foam.

Use fire extinguishing methods suitable to surrounding conditions.

Unsuitable extinguishing media which must not be uses for safety reasons: Strong water jet.

5.2. Special hazards arising from the substance or mixture

Substance is highly flammable. Formation of explosive vapour/air mixtures possible.

Vapours are heavier than air and may spread along the floor.

Hazardous decomposition products: In case of fire, formation of toxic gases/vapours is possible, e.g. carbon monoxide, carbon dioxide.

5.3. Advice for firefighters

If possible, remove endangered containers out of the danger area. Heating leads to pressure increase and danger of rupture/explosion. Cool endangered containers with water spray.

Special protective equipment for fire fighters:

Full protective equipment. Wear self-contained breathing apparatus.

If possible, remove endangered containers out of the danger area. Heating leads to pressure increase and danger of rupture/explosion.

Sufficient measures must be taken to retain water used for extinguishing.

Ignition residues and contaminated water must be disposed of in conformity with local regulations.

Accidental release measures

6.1. Personal precautions, protective equipment and emergency procedures

Do not breathe gas/mist/vapours/spray. Avoid contact with the substance.

Remove all sources of ignition. Take precautionary measures against electrostatic discharges.

Ensure sufficient ventilation. Vapours are heavier than air.

Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.

Avoid formation of aerosols.

Wear personal protective equipment (see Section 8).

Keep unprotected persons away.

6.2. Environmental precautions

Prevent further leaking/release, if this is safely possible.

Do not allow to enter into surface water or drains.

Do not allow to enter into soil.

6.3. Methods and material for containment and cleaning up

Bunding of bigger quantities and pumping into suitable containers.

Minor quantities: soak up with inert absorbent (e.g. kieselguhr or universal binder).

Collect in closed and suitable containers for recycling or disposal.

Contaminated material: dispose of as waste according to section 13.

6.4. Reference to other sections

Safe handling: see Section 7. Personal protective equipment: see Section 8. Disposal: see Section 13 of SDS.

Handling and storage

7.1. Precautions for safe handling:

Keep container tightly closed. Keep away from sources of ignition - No smoking. (Vapours may form explosive mixture with air).

Ensure good ventilation / exhaustion at the workplace.

Provide good room ventilation even at ground level (vapours are heavier than air).

Take measures against electrostatic discharges.

No welding. Work on containers and pipelines is permitted only after thorough purging and inerting.

Avoid formation of aerosols.

Do not breathe vapour/aerosol. Avoid contact with eyes, skin and clothing.

Make available sufficient washing facilities at the workplace. Provide eye shower.

In case of working with bigger quantities, provide emergency shower.

General hygienic measures:

Do not to eat, drink and smoke in work areas;

Wash hands after use;

Separate storage of work clothes.

7.2. Conditions for safe storage, including any incompatibilities:

Keep the packing tightly closed and store in cool and dry area with good ventilation.

Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Moisture sensitive.

Handle and store under dry inert gas.

Protect from heat and direct sunlight.

Store away from sources of ignition, strong oxidising agents, acids, and water.

Store away from pharmaceutical products, food, beverages and feedingstuff.

Provide solvent-resistant, sealed floor.

Observe TRGS 510.

Recommended storage temperature: +5 °C to +25 °C.

Recommended packaging material: HDPE.

Storage class (TRGS 510): 3 (flammable liquid substances).

7.3. Specific end uses(s): Intermediate, water scavenger for moisture curing systems, Laboratory chemical.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

8.1. Control parameters:

Components with occupational exposure limits requiring monitoring:

Austria:

Substance

CAS

MAK or TRK

Toxic for reproduction

Carcinogenic

Limit value

H, S

Remark

TMW

KZW

Duration [min]

Frequency per shift

[ppm]

[mg/m³]

[ppm]

[mg/m³]

Methanol

[67‐56‐1]

MAK

200

260

800

1040

15(Miw)

4x

H

Methyl acetate

[79‐20‐9]

MAK

200

610

400

1220

5(Mow)

8x

n‐Hexane

[110‐54‐3]

MAK

f

20

72

80

288

15(Miw)

4x

Belgium (BELGISCH STAATSBLAD — 14.03.2002 — Ed. 2)

EINECS-nr.

CAS-nr.

Naam van de agentia

Grens-waarde ppm

Grens-waarde mg/m³

Korte-tijdswaarde ppm

Korte-tijdswaarde mg/m³

Bijkomende indeling

200-659-6

00067-56-1

Methanol

200

266

250

333

D

201-185-2

00079-20-9

Methylacetaat

200

615

250

768

203-777-6

00110-54-3

n-Hexaan

50

179

*

*

Germany (TRGS 900, version dated 24.06.2016):

Substance identity

Occupational Exposoure Limit value

Peak limit

Remarks

Name

EC-Nr.

CAS No.

ml/m3 (ppm)

mg/m3

Überschreitungs-faktor

Methanol

200-659-6

67-56-1

200

270

4(ΙΙ)

DFG, EU, H, Y

Methyl acetate

201-185-2

79-20-9

200

610

4(ΙΙ)

DFG, Y

n-Hexane

203-777-6

110-54-3

50

180

8(ΙΙ)

DFG, EU, Y

Switzerland (SUVA 2012):

MAK-Wert

Kurzzeitgrenzwerte

HSB

C

M

RF

RE

SS

Messmethoden/

Stoff [CAS-Nummer]

ml/m³ (ppm)

mg/m³

ml/m³ (ppm)

mg/m³

Zeitl. Begren- zung (Häufig- keit x Dauer in min./Schicht)

besondere Bemerkungen

Methanol [67-56-1]

200

260

800

1040

4 x15

H B

C

INRS, NIOSH

Methylacetat [79-20-9]

100

310

400

1240

4x15

C

INRS, NIOSH

Hexan (n-Hexan) [110-54-3]

50

180

400

1440

4x15

H B

3

C

NIOSH

DNEL (workers): No data available.

DNEL (general population): No data available.

PNEC: No data available.

8.2. Exposure controls

8.2.1. Appropriate engineering controls

Technical measures and appropriate working procedures should be given priority over the use of personal protective equipment. See section 7.

8.2.2 Individual protection measures

Personal protective equipment:

Eye protection: Tightly sealed goggles (EN 166)

Protection of hands:protective gloves.

To avoid skin problems, reduce the wearing of gloves to the required minimum.

The protective gloves must comply with the specifications of EC-Directive 89/686/EEC and the corresponding norm EN 374 (in connection with DIN EN 420 and DIN EN 388).

The glove material has to be impermeable and resistant to the product/ the substance.

Due to missing tests no recommendation to the glove material can be given for the product / the chemical mixture.

Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation.

Glove material:

The selection of suitable gloves does not only depend on the material, but also on further quality characteristics and varies from manufacturer to manufacturer.

Penetration time of glove material:

The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

Body protection:protective clothing.

Protective clothing needs to be selected specifically for the workplace, depending on the concentrations and

quantities of the hazardous substances handled.

Respiratory protection:

Not necessary if exhaust ventilation at the workplace is working well.

Respiratory protection:is needed if technical suction / ventilation measures are not possible or not sufficient, and if treshold limits are exceeded.

In case of short-term or low exposure: use filtering device. Respirator type: filter A.

Observe the wear time limits according to GefStoffV in combination with the rules for using respiratory protection apparatus (BGR 190).

8.2.3 Environmental exposure controls

Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

Stability and reactivity

10.1. Reactivity

No data available.

10.2. Chemical stability

Moisture sensitive.

Stable under recommended conditions of storage and absence of incompatible materials / conditions to avoid.

10.3. Possibility of hazardous reactions

Vapours may form explosive mixture with air.

Violent reaction / explosion with strong oxidizing agents possible.

10.4. Conditions to avoid

Sources of ignition (flames, sparks, static discharges) heat, direct sunlight.

Exposure to moisture.

Do not overheat in order to avoid thermal decomposition.

Avoid formation of aerosols.

10.5. Incompatible materials

Acids

Strong oxidising agents

Water/moisture

10.6. Hazardous decomposition products

In case of hydrolysis with water/moisture: methanol and methyl acetate.

Hazardous combustion products: see Section 5.

Disposal considerations

13.1. Waste treatment methods:

Product:

Disposal according to local regulations. This material may be disposed of only by a licensed waste management company.

Do not allow product to reach sewage system or water courses. Do not dispose of into sewage system.

Do not allow product to enter the soil.

Uncleaned packaging:

Recommendation: Disposal must be made according to official regulations.

The allocation of waste identity numbers/waste descriptions must be carried out according to the EWC,

specific to the industry and process.

Community provisions relating to waste:

1. Directive 2008/98/EC of the European Parliament and of the Council of 19 November 2008 on waste and repealing certain Directives; Official Journal of the European Union, L 312 of 22.11.2008, page 3 - 30.

2. Directive 2006/12/EC of the European Parliament and of the Council of 5 April 2006 on waste,

Official Journal of the European Union, L 114 of 27.04.2006, page 9 – 21.

3. Regulation (EC) No 1013/2006 of the European Parliament and of the Council of 14 June 2006 on shipments of waste; Official Journal of the European Union L 190, 12.7.2006, p. 1–98

4. Local official regulations.