Registration Dossier
Registration Dossier
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EC number: 242-149-6 | CAS number: 18268-70-7
Endpoint summary
Administrative data
Description of key information
Short-Term Toxicity to Fish:
The 96-hour LC50 for rainbow trout (Oncorhynchus mykiss) exposed to the test substance was estimated to be > the water soluble fraction (WSF) of 100 mg/L.Structurally similar substances from a category of aliphatic esters submitted under the High Production Volume (HPV) Chemical Challenge Program (ACC, 2003).were uniformly of low acute aquatic toxicity to fish at or above the nominal water solubility limits.
Short-Term Toxicity to Aquatic Invertebrates:
The estimated 48 -h EC50 value for the test substance corresponded to the WSF of 140 mg/L, with 95 % confidence limits of the WSF of 84 to 250 mg/L.Structurally similar substances from a category of aliphatic esters submitted under the High Production Volume (HPV) Chemical Challenge Program (ACC, 2003).were uniformly of minimal to low acute aquatic toxicity to Daphnia magna at or above the nominal water solubility limits..
Toxicity to Aquatic Algae
For hazard assessment purposes, the toxicity of heptanoic acid, ester with 2,2,4 -trimethyl-1,3 -pentanediol (CAS 71839 -38 -8) was chosen as the most reliable estimate of the value for the algal toxicity of the test substance. It had a reported 72-hr EC50 >2000 mg/L (WAF, nominal loading rate) and a NOEC of 2000 mg/L based on both area under the growth curves and specific growth rates. The latter study was conducted following GLP and according to OECD 201.
Toxicity to Microorganisms:
Based on a limited water solubility and estimated rapid biodegradation, the test substance is expected to have little or no toxicity toward activated sludge microorganisms.
Additional information
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