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EC number: 947-384-4
CAS number: -
For detailed information on the results please refer to the attached
report. The results refer to the uncharged molecule.
Hydrolysis of the substance is not expected under environmental
No experimental studies investigating the hydrolysis of the test
item in water are available. QSAR calculations using HYDROWIN v2.00
indicated that the substance does not hydrolyze quickly in the
environment. The calculations revealed a DT50 at pH7 (25 °C) of 55.14
days to > 1 year. Even though some fragments of the target substance are
not available within the model (and substitutes were used instead) this
result is in line with experimental determination of hydrolytic
degradation under acidic acetic (pH 2, 3 and 4) conditions (Okumura et
al., 2011). Okumura et al. investigated the hydrolytic behavior of
sucrose monolaurate and sucrose monostearate. Since sucrose monostearate
is one of the constituents of the target substance, this result can
adequately be used for the assessment. The hydrolytic degradation was
investigated in diluted hydrochloric acid at pH 2, 3 and 4 at 70 °C. At
pH 2 significant hydrolysis of sucrose monostearate was recorded
wheareas the hydrolytic degradation decreased significantly at pH 3. At
pH 4 almost no hydrolytic degradation could be measured. A
re-calculation from 70 °C to 25 °C indicated a lifetime of sucrose
monostearate of approx. 12 years. Since the hydrolytic degradation
significantly changed from the conditions at pH 2 to pH 4 it was assumed
that sucrose monostearate is hydrolytically stable under neutral
conditions. Even though the hydrolytic stability of higher esterified
esters was not tested it was concluded by the authors of the study that
hydrolysis is assumed to be much slower with higher esterification.
Since the glycosidic bond is sterically more protected by the increased
number of bulky di- and triesters the substance is assumed to have an
even higher stability to hydrolytic degradation.
In conclusion, sucrose mono-, di- and triesters are assumed to be
hydrolytically stable under environmental conditions.
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