Registration Dossier
Registration Dossier
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EC number: 225-690-2 | CAS number: 5011-34-7
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20 sept 2017 to 12 Oct 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- Trimetazidine
- EC Number:
- 225-690-2
- EC Name:
- Trimetazidine
- Cas Number:
- 5011-34-7
- Molecular formula:
- C14H22N2O3
- IUPAC Name:
- 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine
- Test material form:
- liquid
- Details on test material:
- No details are provided in the study report
Constituent 1
- Specific details on test material used for the study:
- Batch: 18128536
Purity: 89.1%
Results and discussion
Boiling point
- Key result
- Boiling pt.:
- ca. 301 °C
- Atm. press.:
- ca. 101 kPa
Applicant's summary and conclusion
- Conclusions:
- The test item has been determined to boil from approximately 301 °C (574 K) at 101.0 kPa.
- Executive summary:
The general physico-chemical properties of TMZ Base have been determined. The results are
summarized below:
Boiling Point. From approximately 301 °C (574 K) at 101.0 kPa, by differential scanning calorimetry, designed to be compatible with Method A.2 Boiling Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
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