Registration Dossier
Registration Dossier
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EC number: 255-078-0 | CAS number: 40783-05-9
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1974
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
- Report date:
- 1975
Materials and methods
- Principles of method if other than guideline:
- BASF-Test
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 2,2'-(2,5-dichloro-1,4-phenylene)bis(1H-anthra[1,2-d]imidazole-6,11-dione)
- EC Number:
- 255-078-0
- EC Name:
- 2,2'-(2,5-dichloro-1,4-phenylene)bis(1H-anthra[1,2-d]imidazole-6,11-dione)
- Cas Number:
- 40783-05-9
- Molecular formula:
- C36H16Cl2N4O4
- IUPAC Name:
- 2-(2,5-dichloro-4-{6,11-dioxo-1H,6H,11H-anthra[1,2-d]imidazol-2-yl}phenyl)-1H,6H,11H-anthra[1,2-d]imidazole-6,11-dione
- Test material form:
- solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- no data
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- water
- Remarks:
- 50%
- Doses:
- 2500 mg/kg bw
- No. of animals per sex per dose:
- no data
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 14 days
- Frequency of observations and weighing: clinical signs daily, weighing weekly
- Necropsy of survivors performed: yes
- Other examinations performed: clinical signs - Statistics:
- n.a.
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 2 500 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- not determinable due to absence of adverse toxic effects
- Mortality:
- no mortality occurred
- Clinical signs:
- no effects
- Body weight:
- no data
- Gross pathology:
- no effects
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The LD50 dermal (rat) was determined to be >2500 mg/kg bw. The substance is not classifiable according to CLP criteria.
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