Registration Dossier
Registration Dossier
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EC number: 807-619-2 | CAS number: 65535-29-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1996
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- no
- Remarks:
- Draft report
- Type of method:
- flask method
- Key result
- Water solubility:
- 1.14 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 15 other: mg/5 mL double destilled water
- Incubation duration:
- 18 d
- Temp.:
- 20 °C
- pH:
- 6.1
- Details on results:
- According to X-ray powder diffraction the starting material and the insoluble residue isolated from water consisted of the same solid state form.
- Conclusions:
- The water solubility was 0.00114 g/L (+/- 0.00013 g/L) measured at 20 °C. The pH value of the saturated water solutions was determined to be 6.1.
- Executive summary:
The water solubility was determined using the flask method at 20 °C according to the guidance A.6 of the European Community (Appendix to the guidelines 92/69/EWG, dated July 31, 1992). The water solubility with 95 % confidence interval obtained after equilibration at 20 °C and separation from the insoluble residues was 0.00114 g/L (+/- 0.00013 g/L) measured at 20 °C. The pH value of the saturated water solutions was determined to be 6.1. According to X-ray powder diffraction the starting material and the insoluble residue isolated from water consisted of the same solid state form.
Reference
Description of key information
The water solubility was 0.00114 g/L (+/- 0.00013 g/L) measured at 20 °C.
Key value for chemical safety assessment
- Water solubility:
- 1.14 mg/L
- at the temperature of:
- 20 °C
Additional information
The pH value of the saturated water solutions was determined to be 6.1.
According to X-ray powder diffraction the starting material and the insoluble residue isolated from water consisted of the same solid state form.
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