Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-748-4
CAS number: 1226911-69-8
7.2.2/1: Exposure Chamber Concentration
test atmosphere was sampled seventeen times during the exposure period
and the actual concentration of the test item calculated. The mean
values obtained were:
Mean Achieved (mg/L)
chamber flow rate was maintained at 60 L/min providing 120 air changes
theoretical chamber equilibration time (T99) was 3 minutes (Silver,
7.2.2/2: Particle Size Distribution
Mean Achieved Atmosphere Concentration (mg/L)
Mean Mass Median Aerodynamic Diameter (μm)
(% <4 μm)
Geometric Standard Deviation
an acute inhalation toxicity study performed according to OECD Guideline
436, groups (3/sex/dose) of RccHanTM:
WIST strain rats were exposed (nose only) to aerosol atmosphere of ST 01
C 11 at concentration of 5.31 mg/L (mean achieved) for 4 h. Animals were
observed for mortality, clinical signs and body weight for 14 days and
at the end of the study the animals were sacrificed for macroscopic
mortality was observed. Common abnormalities noted during the study
included increased respiratory rate, hunched posture, pilo-erection and
wet fur. Isolated occurrences of red/brown staining around the eyes or
snout were also noted. Animals recovered to appear normal from Days 8 to
10 post-exposure. Two male and two female animals exhibited slight
bodyweight losses on the first day post-exposure. Reasonable bodyweight
development was noted in all male animals during the remainder of the
recovery period. In contrast, two female animals exhibited bodyweight
losses from Days 1 to 3 post-exposure. Bodyweight gains were noted in
all female animals for the remainder of the recovery period. No
macroscopic abnormalities were detected amongst animals at necropsy.
(4 hours) combined > 5.31 mg/L
the test conditions, the inhalation LC50 for ST 01 C 11 is higher than
5.31 mg/L for 4 h in rats and therefore it is not classified according
to Regulation (EC) No. 1272/2008 (CLP) and to GHS.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again