Reaction product of D-Glucopyranoside, methyl; esterified with oleic acid, methyl ester

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2015-04-02 - 2015-06-02

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

comparable to guideline study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

The Department of Health of the Government of the United Kingdom

Type of method:

differential scanning calorimetry

Key result

Decomposition:

yes

Decomp. temp.:

ca. 200 °C

Remarks on result:

other:

Remarks:

at 99 kPa

The thermograms and thermographic data for determinations 1 to 3 are shown in figures (see attachment) and table:

Thermal Event	Interpretation	Temperature [°C (K)]
		Determination 1	Determination 2	Determination 3
Exotherm	Onset of decomposition	200.31 (473.46)	206.88 (480.03)	209.81 (482.96)

Atmospheric pressure: 99 kPa

After being heated to 400 °C, the residues of the three determinations had lost approximately 36 % and 42 % of their original weight.

Overall result: decomposition from approximately 200 °C (473 K)

Discussion

As a result of the low rate of enthalpy change during decomposition, the onset temperature could only be approximated. As approximately 60% remained after heating to 400 °C, complete decomposition and volatilization of the test item had not occurred.

The baseline shift between approximately 160 and 170 °C in Determination 1 was considered not to be a thermal event related to the test item. Thus, a third determination was performed to confirm this.

Conclusion

The test item has been determined to decompose from approximately 200 °C (473 K) at 99 kPa. As the test item decomposed, no value for boiling temperature could be determined.

Conclusions:

The test item has been determined to decompose from approximately 200 °C (473 K) at 99 kPa. As the test item decomposed, no value for boiling temperature could be determined.

Executive summary:

The boiling point of the test item was determined to a procedure compatible with EU Method A.2 and OECD Guideline 103 in compliance with GLP. Differntial scanning calorimetry was chosen as method. After being heated to 400°C, the residues had lost approximately 36 % and 42 % of their original weights.

As a result of the low rate of enthalpy change during decomposition, the onset temperature could only be approximated. As approximately 60% remained after heating to 400 °C, complete decomposition and volatilization of the test item had not occurred. The baseline shift between approximately 160 and 170 °C in Determination 1 was considered not to be a thermal event related to the test item. Thus, a third determination was performed to confirm this. Conclusively, the test item has been determined to decompose from approximately 200 °C (473 K) at 99 kPa. As the test item decomposed, no value for boiling temperature could be determined.

Description of key information

The boiling point of the test item was determined to a procedure compatible with EU Method A.2 and OECD Guideline 103 in compliance with GLP. Differntial scanning calorimetry was chosen as method. After being heated to 400°C, the residues had lost approximately 36 % and 42 % of their original weights.

As a result of the low rate of enthalpy change during decomposition, the onset temperature could only be approximated. As approximately 60% remained after heating to 400 °C, complete decomposition and volatilization of the test item had not occurred. The baseline shift between approximately 160 and 170 °C in Determination 1 was considered not to be a thermal event related to the test item. Thus, a third determination was performed to confirm this. Conclusively, the test item has been determined to decompose from approximately 200 °C (473 K) at 99 kPa.

The test item has been determined to decompose from approximately 200 °C (473 K) at 99 kPa. As the test item decomposed, no value for boiling temperature could be determined.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

200 °C