Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 944-723-8 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Skin sensitising in Guinea pigs.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
According to the CLP Regulation (EC 1272/2008), skin sensitizer is a substance that will lead to an allergic response following skin contact. In case of a guinea pig maximisation test, a response of at least 30 % of the animals, after intradermal induction at concentration of > 1 %, is considered as positive.
Under the experimental conditions employed, 60 % and 100 % of the animals of the test group showed skin reactions 24 and 48 hours upon challenge, respectively. Intradermal induction was done with 5 % test substance concentration. On these bases, classification applied. Based on the read across approach, the substance was considered as skin sensitising and classified in category 1B of the CLP Regulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
