Registration Dossier
Registration Dossier
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EC number: 701-090-0 | CAS number: -
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: early study, limited documentation
Data source
Reference
- Title:
- No information
- Author:
- Miller JW, Sayers RR (1934). The physiological response of the peritoneal tissue to dust intrdoced as foreign bodies. Publ Health Rep 49, 80-89.
Materials and methods
- Type of study / information:
- Type: other: intraperitoneal injection; local reaction
- Principles of method if other than guideline:
- Guinea pig, single i.p. injection of 200 mg ferric oxide (no further data), observation period 7,14, 30, or 90 days
- GLP compliance:
- no
Test material
- Reference substance name:
- Diiron trioxide
- EC Number:
- 215-168-2
- EC Name:
- Diiron trioxide
- Cas Number:
- 1309-37-1
- Molecular formula:
- Fe2O3
- IUPAC Name:
- Diiron trioxide
- Details on test material:
- no data
Constituent 1
Results and discussion
Any other information on results incl. tables
Nodules became flattened, and many dust particles were extensively disseminated throughout the peritoneum as the time interval between injection and examination lenghthened
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
