Registration Dossier
Registration Dossier
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EC number: 217-992-8 | CAS number: 2033-24-1
Genetic toxicity: in vivo
Administrative data
- Endpoint:
- in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- see attached OECD Toolbox study
Data source
Reference
- Title:
- No information
- Author:
- Anonymous
- Year:
- 2 016
- Bibliographic source:
- OECD Toolbox v3.4.0.17
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
- GLP compliance:
- not specified
- Type of assay:
- other: genetic toxicity in vivo
Test material
- Reference substance name:
- 2,2-dimethyl-1,3-dioxane-4,6-dione
- EC Number:
- 217-992-8
- EC Name:
- 2,2-dimethyl-1,3-dioxane-4,6-dione
- Cas Number:
- 2033-24-1
- Molecular formula:
- C6H8O4
- IUPAC Name:
- 2,2-dimethyl-1,3-dioxane-4,6-dione
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
Results and discussion
Test results
- Key result
- Sex:
- male/female
- Genotoxicity:
- negative
- Toxicity:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
