Registration Dossier
Registration Dossier
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EC number: 943-932-1 | CAS number: 26834-28-6
Endpoint summary
Administrative data
Description of key information
Studies on acute oral toxicity are available on LiDNNSA, DNNSA and BaDNNSA. These studies are indicative of low toxicity (LD50 > 2500 mg/kg bw) and show that LiDNNSA, DNNSA and BaDNNSA are suitable candidates for read-across.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- discriminating dose
- Value:
- 2 500 mg/kg bw
- Quality of whole database:
- Information is sufficient to be used for classification and labelling
Additional information
The available studies contain sufficient information to be used for risk assessment and classification and labelling. All tests are performed on formulations. The effect levels are based on active ingredient, as it is not expected that the diluent has contributed to the effects that were observed.
Justification for selection of acute toxicity – oral endpoint
Studies on analogues were conducted prior to GLP regulations but used methods generally consistent with accepted procedures. All studies are of equal quality and can be used in a weight of evidence. The results of these studies are comparable. some mortality and effects were noted at 2500 mg/kg bw.
Justification for classification or non-classification
Based on the outcome of the studies no classification for acute oral toxicity is proposed.
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