Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 208-523-8 | CAS number: 532-02-5
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data is from modelling database developed by the National Food Institute, Technical University of Denmark.
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 532-02-5
- Author:
- Danish (Q)SAR Database
- Year:
- 2 016
- Bibliographic source:
- Database developed by National Food Institute, Technical University of Denmark, with support from the Danish Environmental Protection Agency, the Nordic Council of Ministers and the European Chemicals Agency.
Materials and methods
- Principles of method if other than guideline:
- Data is predicted using the Danish (Q)SAR Database
- GLP compliance:
- no
- Test type:
- standard acute method
Test material
- Reference substance name:
- Sodium naphthalene-2-sulphonate
- EC Number:
- 208-523-8
- EC Name:
- Sodium naphthalene-2-sulphonate
- Cas Number:
- 532-02-5
- Molecular formula:
- C10H8O3S.Na
- IUPAC Name:
- sodium naphthalene-2-sulphonate
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- SMILES: c12c(cc(S(=O)(=O)O)cc1)cccc2
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 4 100 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: estimated data
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Based on the QSAR prediction done using the Danish (Q)SAR Database, the LD50 was estimated to be 4100 mg/kg bw on rat for substance Sodium naphthalene-2-sulphonate. Thus based on this value it can be concluded that the substance can be classified as non toxic as per the criteria of CLP regulation.
- Executive summary:
Based on the QSAR prediction done using the Danish (Q)SAR Database, the LD50 was estimated to be 4100 mg/kg bw on rat for substance Sodium naphthalene-2-sulphonate. Thus based on this value it can be concluded that the substance can be classified as non toxic as per the criteria of CLP regulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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