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EC number: 235-440-4 | CAS number: 12227-78-0
Endpoint summary
Administrative data
Description of key information
Appearance/physical state/colour:
On the basis of physical observation and using the sense of smell, test chemical was observed to be a red colored powder.
Melting point/freezing point:
The melting point determination of Test chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was done as per the test guideline OECD 102. The method followed was according to Capillary/metal block. The Mean melting temperature range was determine to be 228 °C -233.5°C at 968.9 hPa.
Boiling point:
The boiling point of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2) was predicted using MPBPVP (v1.43) Program Results of EPI suite.
The boiling point of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2)
was estimated to be 726.15 deg C .
Density :
The mean density of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was determined following OECD Guideline 109 and according to the method adapted from ASTM D 854-02. The mean density of the test item was determied to be 2.024 g/cm3 at 20° C and 967.5 hPa.
Particle size distribution (Granulometry):
The particle size distribution of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 microns to 10 microns.
Vapour pressure:
The vapour pressure of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2) is found to be 6.15E-020 mm Hg (Modified Grain Method) 8.19E-018 Pa (Modified Grain Method) at 25 deg C.
Partition coefficient:
Water solubility:
The water solubility of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2) was predicted to be 3.27e-006 mg/L. This value indicates that the substance is insoluble in water.
Solubility in organic solvents/fat solubility:
Surface tension:
In accordance with column 2 of Annex VII of the REACH regulation, the study need only be conducted if surface activity is a desired property of the chemical. The chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt is widely used as a food colour. For this use, surface activity is not a desired property. Hence this study was considered for waiver.
Flash point:
The flash point of Test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) is 221.66 °C at 966.1 hPa.
Auto flammability:
The chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (Common Name: C.I. Pigment Red 172) does not catch fire sponstaneously when exposed to air at normal conditions of temperature and pressure. Thus, this end point was considered for waiver and the chemical is not very likely to be "Auto Flammable".
Flammability:
The NFPA rating for Flammability of the chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (Common Name: C.I. Pigment Red 172) varies from 0 to 1 indiacting that the chemical is not very likely to be "Flammable". Thus, this end point was considered for waiver, since the chemical is most likely to be "Non-flammable".
Explosiveness:
In accordance with column 2 of Annex VII of the REACH regulation, there are no chemical groups associated with explosive properties present in the molecule of the chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (Common Name: C.I. Pigment Red 172). Thus, the chemical is unlikely to be explosive.
Oxidising properties:
In accordance with column 2 of Annex VII of the REACH regulation, the substance 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (Common Name: C.I. Pigment Red 172) is incapable of reacting exothermically with combustible materials on the basis of the chemical structure. It is an organic substance containing oxygen or iodine and these elements are not chemically bonded to nitrogen or oxygen. Thus, the chemical is not expected to exhibit oxidising property.
pH:
The pH determination of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was done as per the test guideline OECD 122. The mean pH of the test dispersion was determined with the help of digital pH meter. The mean pH was determine to be 4.30 at 33 °C.
Additional information
Appearance/physical state/colour:
On the basis of physical observation and using the sense of smell, test chemical was observed to be a red colored powder.
Melting point/freezing point:
The melting point determination of Test chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was done as per the test guideline OECD 102. The method followed was according to Capillary/metal block. The Mean melting temperature range was determine to be 228 °C -233.5°C at 968.9 hPa.
Boiling point:
The boiling point of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2) was predicted using MPBPVP (v1.43) Program Results of EPI suite.
The boiling point of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2)
was estimated to be 726.15 deg C .
Density:
The mean density of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was determined following OECD Guideline 109 and according to the method adapted from ASTM D 854-02. The mean density of the test item was determied to be 2.024 g/cm3 at 20° C and 967.5 hPa.
Particle size distribution (Granulometry):
The particle size distribution of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 microns to 10 microns.
Vapour pressure :
The vapour pressure of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2) was predicted using MPBPVP (v1.43) Program Results of EPI suite.
The vapour pressure of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2) is found to be 6.15E-020 mm Hg (Modified Grain Method) 8.19E-018 Pa (Modified Grain Method) at 25 deg C.
Partition coefficient :
The partition coefficient of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4',5',7'-tetraiodo-, aluminum salt (3:2) was predicted using KOWWIN Program (v1.68) Results of EPI suite.
The partition coefficient of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2) was predicted to be Log Kow = 8.0195.
Water solubility :
The water solubility of chemical Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4 ',5',7'-tetraiodo-, aluminum salt (3:2) was predicted to be 3.27e-006 mg/L. This value indicates that the substance is insoluble in water.
Solubility in organic solvents/fat solubility:
Surface tension:
In accordance with column 2 of Annex VII of the REACH regulation, the study need only be conducted if surface activity is a desired property of the chemical. The chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt is widely used as a food colour. For this use, surface activity is not a desired property. Hence this study was considered for waiver.
Flash point :
The flash point determination of of 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt(CAS No.12227-78-0)was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was determined to be 221.66 °C at 966.1 hPa.
Auto flammability :
The chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (Common Name: C.I. Pigment Red 172) does not catch fire sponstaneously when exposed to air at normal conditions of temperature and pressure. Thus, this end point was considered for waiver and the chemical is not very likely to be "Auto Flammable".
Flammability :
The NFPA rating for Flammability of the chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (Common Name: C.I. Pigment Red 172) varies from 0 to 1 indiacting that the chemical is not very likely to be "Flammable". Thus, this end point was considered for waiver, since the chemical is most likely to be "Non-flammable".
Explosiveness :
In accordance with column 2 of Annex VII of the REACH regulation, there are no chemical groups associated with explosive properties present in the molecule of the chemical 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (Common Name: C.I. Pigment Red 172). Thus, the chemical is unlikely to be explosive.
Oxidising properties :
In accordance with column 2 of Annex VII of the REACH regulation, the substance 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (Common Name: C.I. Pigment Red 172) is incapable of reacting exothermically with combustible materials on the basis of the chemical structure. It is an organic substance containing oxygen or iodine and these elements are not chemically bonded to nitrogen or oxygen. Thus, the chemical is not expected to exhibit oxidising property.
pH :
The pH determination of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was done as per the test guideline OECD 122. The mean pH of the test dispersion was determined with the help of digital pH meter. The mean pH was determine to be 4.30 at 33 °C.
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