Registration Dossier
Registration Dossier
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EC number: 411-540-5 | CAS number: 130201-57-9 REACTIVE RED SR 6947; ROUGE REACTIF SR 6947
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 84/449 EEC, B5
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Tetrasodium 5-[4-chloro-6-(N-ethyl-anilino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(1,5-disulfonatonaphthalen-2-ylazo)-naphthalene-2,7-disulfonate
- EC Number:
- 411-540-5
- EC Name:
- Tetrasodium 5-[4-chloro-6-(N-ethyl-anilino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(1,5-disulfonatonaphthalen-2-ylazo)-naphthalene-2,7-disulfonate
- Cas Number:
- 130201-57-9
- Molecular formula:
- C31H20ClN7Na4O13S4
- IUPAC Name:
- tetrasodium 5-[4-chloro-6-(N-ethyl-anilino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(1,5-disulfonatonaphthalen-2-ylazo)-naphthalene-2,7-disulfonate
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Amount / concentration applied:
- MG
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- overall irritation score
- Basis:
- animal: No. 57, male
- Time point:
- other: overall at 1, 24, 48 and 72 h
- Score:
- >= 0 - <= 1
- Irritation parameter:
- overall irritation score
- Basis:
- animal: No. 58, male
- Time point:
- other: overall at 1, 24, 48 and 72 h
- Score:
- >= 0 - <= 1
- Irritation parameter:
- overall irritation score
- Basis:
- animal: No. 59, female
- Time point:
- other: overall at 1, 24, 48 and 72 h
- Score:
- >= 0 - <= 1
Any other information on results incl. tables
EYE IRRITATION SCORES
ANIMAL SEX CORNEA IRIS CONJUNCTIVAE CUMULATIVE MEAN CUMULATIVE
OPACITY REDN. CHEM. SCORE SCORE
1 HR.
57 M NOT RINSED 0 0 0 1 1
58 M NOT RINSED 0 0 0 1 1
59 F NOT RINSED 0 0 0 1 1 1.00
24 HRS.
57 M NOT RINSED 0 0 0 1 1
58 M NOT RINSED 0 0 0 0 0
59 F NOT RINSED 0 0 0 1 1 0.67
48 HRS.
57 M NOT RINSED 0 0 0 1 0
58 M NOT RINSED 0 0 0 0 0
59 F NOT RINSED 0 0 0 1 0 0.00
72 HRS.
57 M NOT RINSED 0 0 0 1 0
58 M NOT RINSED 0 0 0 0 0
59 F NOT RINSED 0 0 0 1 0 0.00
Applicant's summary and conclusion
- Interpretation of results:
- other: not classified
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