1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-4H-inden-4-one

Toxicity to soil macroorganisms except arthropods

Administrative data

Endpoint:

toxicity to soil macroorganisms except arthropods: long-term

Type of information:

experimental study planned

Study period:

Planned for 2022

Justification for type of information:

Based on grounds for concern regarding potential persistency of the substance, an Earthworm reproduction test (Eisenia fetida/Eisenia andrei) OECD TG 222 will be initiated to confirm (lack of) risk (from the EPM screening) in the soil compartment. As specified in ECHA Guidance on IR&CSA, R.7C: “When the substance is also readily degradable, biotically or abiotically, however, and has a log Kow <5, this screening assessment showing no risk using aquatic toxicity data is sufficient to obviate the need for further information under Annex IX. In other circumstances, the derivation of a PNECscreen derived from aquatic toxicity data alone would be insufficient to derogate from Annex IX or X testing.” Testing is scheduled for 2022.

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 222 (Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei))

Version / remarks:

29 July 2016

Test material

Test material information

Constituent 1

Reference substance name:

1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-4H-inden-4-one

EC Number:

251-649-3

EC Name:

1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-4H-inden-4-one

Cas Number:

33704-61-9

Molecular formula:

C14H22O

IUPAC Name:

1,1,2,3,3-pentamethyl-2,3,4,5,6,7-hexahydro-1H-inden-4-one

Test organisms

Test organisms (species):

Eisenia fetida

Animal group:

annelids

Study design

Study type:

laboratory study

Total exposure duration:

28 d