Registration Dossier
Registration Dossier
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EC number: 271-516-3 | CAS number: 68583-51-7
Endpoint summary
Administrative data
Description of key information
The hazard assessment is based on the data currently available. New studies with the registered substance and/or other member substances of the glycol esters category will be conducted in the future. The finalised studies will be included in the technical dossier as soon as they become available and the hazard assessment will be re-evaluated accordingly.
For further details, please refer to the category concept document attached to the category object (linked under IUCLID section 0.2) showing an overview of the strategy for all substances within the glycol esters category.
Additional information
The hazard assessment is based on the data currently available. New studies with the registered substance and/or other member substances of the glycol esters category will be conducted in the future. The finalised studies will be included in the technical dossier as soon as they become available and the hazard assessment will be re-evaluated accordingly.
For further details, please refer to the category concept document attached to the category object (linked under IUCLID section 0.2) showing an overview of the strategy for all substances within the glycol esters category.
Several experimental studies confirmed that decanoic acid, mixed diesters with octanoic acid and propylene glycol (CAS 68583-51-7) is readily biodegradable according to the OECD criteria (82% biodegradation after 28 d). Therefore, the substance will not be persistent in the environment. The degradation via abiotic hydrolysis is not considered to be a relevant degradation pathway in the environment.
Considering the low water solubility (< 0.05 mg/L) and the potential for adsorption to organic soil and sediment particles (log Koc: 3.79 and 5.60, MCI method, KOCWIN v2.01), the main compartment for environmental distribution is expected to be the soil and sediment. Nevertheless, persistency in these compartments is not expected since the substance is readily biodegradable. Evaporation into air and the transport through the atmospheric compartment is not expected since the substance is not volatile based on the low vapour pressure (VP:≤ 0.001 Pa). Accumulation in air and the subsequent transport to other environmental compartments is not anticipated.
Due to the low water solubility, rapid environmental biodegradation and metabolisation via enzymatic hydrolysis of decanoic acid, mixed diesters with octanoic acid and propylene glycol (CAS 68583-51-7), a relevant uptake and bioaccumulation in aquatic organisms is not expected. Enzymatic breakdown will initially lead to the free fatty acid and the free glycol alcohol (e. g. ethylene glycol). From literature it is well known, that these hydrolysis products will be metabolised and excreted in fish effectively (Heymann, 1980; Lech & Bend, 1980; Lech & Melancon, 1980; Murphy & Lutenske, 1990).
For a detailed reference list please refer to the CSR.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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