Registration Dossier
Registration Dossier
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EC number: 915-037-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
There is no data on skin, eye or respiratory irritation for silicocalcium. Therefore, weight of evidence approach is utilised in which the information on the toxicity of constituents and related compounds are used.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
There is no data on skin or eye irritation for silicocalcium. The surface of silicocalcium is composed mainly of silicon and calcium rich oxides. Silicon is released from CaSi at similar or somewhat lower levels than from amorphous silicon dioxide. The release of iron from silicocalcium is very restricted and resembles the release of iron from pyrogenic silica. Thus, amorphous silica is used for read-across in the assessment of the irritation of CaSi. However, since significant levels of calcium are also released from CaSi matrix the impact of this element on the irritation of CaSi should be also assessed.
A large number of silicates (Ca- and Al-silicates among them) are widely accepted for use in cosmetics, and no irritation has been observed.
The weight-of-evidence supports the non-irritancy of silicocalcium.
Justification for classification or non-classification
Conclusion: Silicocalcium is unlikely skin or eye irritant. No classification or further testing is proposed. Naturally, like any other dusts, also the dusts of silicocalcium may cause mechanical irritation of the eye and respiratory tract.
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