Tricobalt tetraoxide

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

no

Type of method:

flask method

Water solubility:

46.8 µg/L

Temp.:

21.5 °C

pH:

6

Remarks on result:

other: Co3O4 concentration at 24 hour sampling time at 100 mg/L loading. Average value from the tests of the four laboratories is given on a log10-scale.

Water solubility:

17.5 µg/L

Temp.:

21.5 °C

pH:

ca. 6

Remarks on result:

other: Co3O4 concentration at 672 hour sampling time at 1 mg/L loading. Average value from the tests of the four laboratories is given on a log10-scale.

Water solubility:

3.32 µg/L

Temp.:

21.5 °C

pH:

ca. 6

Remarks on result:

other: Co3O4 concentration at 168 hour sampling time at 1 mg/L loading. Average value from the tests of the four laboratories is given on a log10-scale.

Water solubility:

33.5 µg/L

Temp.:

21.5 °C

pH:

ca. 6

Remarks on result:

other: Co3O4 concentration at 168 hour sampling time at 10 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.

Water solubility:

169 µg/L

Temp.:

21.5

pH:

ca. 6

Remarks on result:

other: Co3O4 concentration at 168 hour sampling time at 100 mg/L loading. Sample analysis was conducted in triplicate per test vessel (3 test vessels per loading). Average value from the tests is given.

Conclusions:

Under the conditions of the transformation/dissolution test, the dissolution of Co3O4 is 1.03 on a log10-scale at 1 mg/L loading for the 28-day endpoint.
The dissolution of Co3O4 is 1.41 on a log10-scale at 10 mg/L loading for the 7-day endpoint.
The dissolution of Co3O4 is 2.12 on a log10-scale at 100 mg/L loading for the 7-day endpoint.

Executive summary:

A seven day transformation/dissolution test according to the OECD guideline 29 and the GHS (Annex 10) protocol was run on Co3O4 at a mass loading of 10 and 100 mg/L, at a pH of 6.0 Also a 28 day transformation/dissolution was run on Co3O4 at a mass loading of 1 mg/L and at a pH of 6.0. Under the conditions of this test, the dissolution of Co3O4 is 1.03 on a log10 -scale for the 28 -day endpoint (1 mg/L loading), 1.41 on a log10 -scale for the 7 -day endpoint (10 mg/L loading) and 2.12 on a log10 -scale for the 7 -day endpoint (100 mg/L loading).

Reference 2

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2005-08-18 to 2005-09-21

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The stability of the test material was not available.

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

, 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

, 1992

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

signed 2003-03

Type of method:

column elution method

Water solubility:

>= 1.56 - <= 1.68 mg/L

Temp.:

20 °C

pH:

>= 6.96 - <= 7.48

Water solubility:

>= 5.1 - <= 5.56 mg/L

Temp.:

37 °C

pH:

>= 6.62 - <= 7.31

Details on results:

Total elution times were about 93 hours at 20 °C and 115.5 hours at 37 °C. The measured results differ by less than 30 %. Therefore, the study is considered to be valid.
The water solubility was not corrected for the purity of the test item.

Conclusions:

Interpretation of results: slightly soluble (0.1-100 mg/L)
The water solubility of Tricobalt Tetraoxide was found to be at 20°C 1.62 mg/L and at 37°C 5.33 mg/L using the column elution method.

Description of key information

Tricobalt tetraoxide has a water solubility 1.62 mg/L at 20 °C and 5.33 mg/L at 37 °C .

Key value for chemical safety assessment

Water solubility:

1.62 mg/L

at the temperature of:

20 °C