Registration Dossier
Registration Dossier
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EC number: 215-676-4 | CAS number: 1341-49-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No data are available for the substance, ammonium hydrogendifluoride (AMBI). The substance is water-soluble and, in aqueous environments, will dissociate to form hydrogen, fluoride and ammonium ions. Read-across data are available from the soluble fluoride salt, sodium fluoride and from ammonia. Ammonia acts as a nutrient, therefor high endpoints are reported (EC50 of 2700 mg/L) and it is clear that the effects of AMBI will be due to fluoride (EC50 values 43-122 mg/L).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 43 mg/L
- EC50 for marine water algae:
- 81 mg/L
- EC10 or NOEC for freshwater algae:
- 50 mg/L
- EC10 or NOEC for marine water algae:
- 50 mg/L
Additional information
No data are available for the substance, ammonium hydrogendifluoride (AMBI). The substance is water-soluble and, in aqueous environments, will dissociate to form hydrogen, fluoride and ammonium ions. Read-across data are available from the soluble fluoride salt, sodium fluoride and from ammonia.
Fluoride data
The EU RAR for hydrogen fluoride (HF) reviews and summarises the available data on the toxicity of sodium fluoride (NaF) to freshwater and marine algae species. The EC50 values for freshwater algae are reported to range from 43 to 122 mg/L (as fluoride ion, F-). For marine algae the EC50 was 81 mg/L in a single study with Skeletonema costatum. NOEC values of 50 -249 mg/L and 50 -200 mg/L are reported for freshwater and marine algae, respectively. Ammonia data
The effect of ammonia concentration on growth and physiology of a unicellular green alga, Chlorella vulgaris, was studied by Tam & Wong (1996). Algal growth was accompanied by a decrease in nitrogen content in the medium, indicating that nitrogen removal was due to algal uptake and assimilation. Results demonstrate that C. vulgaris can tolerate high concentrations of ammonia. The 18 day EC50 was calculated to be 2700 mg/L.
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