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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Actions of sodium azide
Author:
Graham J.D.P.
Year:
1949
Bibliographic source:
Br J Pharmacol Chemother. 4(1):1-6, PMID: 18113147
Reference Type:
review article or handbook
Title:
Information profile sodium azide
Author:
Gregory A.R.
Year:
1978
Bibliographic source:
NIOSH / DCDSD

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
no
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium azide
EC Number:
247-852-1
EC Name:
Sodium azide
Cas Number:
26628-22-8
Molecular formula:
N3Na
IUPAC Name:
sodium azide

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 28 - < 34 mg/kg bw
Mortality:
no data
Clinical signs:
no data
Body weight:
no data
Gross pathology:
no data

Applicant's summary and conclusion

Conclusions:
In this study, the LD50 (mouse, i.p.) was reported to be 28-34 mg/kg bw.
Executive summary:

In an acute intraperitoneal toxicity study, mice were given a dose of sodium azide. The LD50 (mouse i.p.) was reported to be 28-34 mg/kg bw.