Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 610-199-1 | CAS number: 446292-04-2
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 2006-09-26 to 2006-11-21
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: According to guideline unde GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 4-(4-nitrophenyl)morpholin-3-one
- EC Number:
- 610-199-1
- Cas Number:
- 446292-04-2
- Molecular formula:
- C10 H10 N2 O4
- IUPAC Name:
- 4-(4-nitrophenyl)morpholin-3-one
- Details on test material:
- - Name of test material (as cited in study report): 4-(4-Nitrophenyl)-3-morpholinon
- Analytical purity: 97,5%
- Lot/batch No.: BXR2LPC
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
Any other information on results incl. tables
4-(4-Nitrophenyl)-3-morpholinon showcd: 0.4 % degradation after 7 days, 0.9 % degradation after 14 days, 1.3 % degradation after 21 days and 0.0 % degradation after 28 days.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- 4-(4-Nitrophenyl)-3-morpholinon is considered to be "Not Readily Biodegradable".
- Executive summary:
A study was performed to assess the ready biodegradability of 4-( 4-Nitrophenyl)-3-morpholinon. The study was conducted in accordance with the Council Directive 92/69/EEC Method C.4-D "Manometric Respirometry Test", This test method is in all essential parts identical wirh OECD Guideline 301 F. A solution of 4-(4-Nitrophenyl)-3-morpholinon in a mineral medium was inoculated and incubated for 28 d under aerobic conditions. During this period, degradation was followed by BOD determinations. 4-(4-Nitrophenyl)-3-morpholinon showed: 0.4 % degradation after 7 days, 0.9 % degradation after 14 days, 1.3 % degradation after 21 days and 0.0 % degradation after 28 days. Therefore, 4-(4-Nitrophenyl)-3-morpholinon is considered to be "Not Readily Biodegradable". The reference compound showed 86.3 % degradation after 14 days.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
