Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-563-2 | CAS number: 108-23-6
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 3 (not reliable)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- No information
- Year:
- 1 970
- Bibliographic source:
- British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- v. 27, p. 1, 1970 (RTECS Database)
- Reference Type:
- review article or handbook
- Title:
- No information
- Year:
- 1 992
- Bibliographic source:
- R.J. Lewis, sr., Sax´s Dangerous Properties of Industrial Materials, Eighth Edition, 1992
Materials and methods
- Principles of method if other than guideline:
- Database entry, method not known.
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- Isopropyl chloroformate
- EC Number:
- 203-563-2
- EC Name:
- Isopropyl chloroformate
- Cas Number:
- 108-23-6
- Molecular formula:
- C4H7ClO2
- IUPAC Name:
- propan-2-yl carbonochloridate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- 5 h
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LCLo
- Effect level:
- 200 ppm
- Based on:
- not specified
- Exp. duration:
- 5 h
- Clinical signs:
- other: Lungs, Thorax, or Respiration: Dyspnea
Applicant's summary and conclusion
- Interpretation of results:
- highly toxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
