Registration Dossier
Registration Dossier
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EC number: 233-732-6 | CAS number: 10339-55-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Not specified
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: pre-GLP study
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 967
- Report date:
- 1967
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- No remarks
- GLP compliance:
- no
- Remarks:
- pre-GLP
- Test type:
- other: not specified
- Limit test:
- no
Test material
- Reference substance name:
- 3,7-dimethylnona-1,6-dien-3-ol
- EC Number:
- 233-732-6
- EC Name:
- 3,7-dimethylnona-1,6-dien-3-ol
- Cas Number:
- 10339-55-6
- Molecular formula:
- C11H20O
- IUPAC Name:
- 3,7-dimethylnona-1,6-dien-3-ol
- Details on test material:
- Ethyllinalool, no further information
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- other: CFW
- Sex:
- male
- Details on test animals or test system and environmental conditions:
- Weight: 17-22 g
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- unchanged (no vehicle)
- Details on oral exposure:
- 72 hours observation for mortality
- Doses:
- Not indicated
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
- Details on study design:
- No remarks
- Statistics:
- Not indicated
Results and discussion
- Preliminary study:
- Not indicated
Effect levels
- Key result
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 5 283 mg/kg bw
- Mortality:
- The oral LD50 in mice was determined to be 5283 +/- 383 mg/kg bw.
LD50's were calculated by the method of Miller and Tainter (Proc. Soc. Exptl. Biol. Med. 57:261, 1944). - Clinical signs:
- other: Not indicated
- Gross pathology:
- Not indicated
- Other findings:
- Not indicated
Any other information on results incl. tables
Not relevant
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The substance does not have to be classified according to the classification criteria outlined in 67/548/EEC and 1272/2008/EC.
- Executive summary:
The oral LD50 in mice was determined to be 5283 +/- 383 mg/kg bw.
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