Registration Dossier
Registration Dossier
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EC number: 402-920-1 | CAS number: 103300-89-6 N-6-TRIFLUORACETYL-L-LYSYL-L-PROLIN; T.F.A. LYS PRO; TFA-LYS-PRO
Surface tension
Administrative data
Link to relevant study record(s)
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993-03-19 to 1993-03-19
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Version / remarks:
- 84/449/EEC, A.5 (Ring method)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- ring method
- Key result
- Surface tension:
- 68.7 mN/m
- Temp.:
- 20 °C
- Conc.:
- 1 g/L
- Conclusions:
- In a study according to Directive 84/449/EEC, A.5 (ring method) the surface tension of the test item at a concentration of 1.0 g/L was determined to be 68.7 mN/m at 20 °C, thus the test item is not considered to be surface active.
Reference
Calibration:
measured value [mN/m] |
mean value [mN/m] |
calibration factor |
72.9 |
72.73 |
1.0009 |
72.7 |
||
72.6 |
Main Test Results:
Test No. |
Time [min] |
measured value [mN/m] |
1 |
0 |
61.5 |
2 |
7 |
67.3 |
3* |
12 |
68.7 |
4* |
15 |
68.7 |
5* |
18 |
68.9 |
6* |
25 |
68.9 |
*) only the last four measured values were used to calculate the mean value.
Mean value [mN/m] : 68.8
Mean value * calibration factor : 68.9
Corrected value according to Harkins - Jordan
(DIN 53914, table in EEC-Guideline A.5) : 68.65
Description of key information
Not surface active (68.7 mN/m at 1 g/L and 20 °C; EEC method A.5. (ring method), GLP)
Key value for chemical safety assessment
- Surface tension:
- 68.7
- in mN/m at 20°C and concentration in mg/L:
- 1 019.5
Additional information
In a study according to Directive 84/449/EEC, A.5 (ring method) the surface tension of the test item at a concentration of 1.0 g/L was determined to be 68.7 mN/m at 20 °C, thus the test item is not considered to be surface active.
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