Registration Dossier
Registration Dossier
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EC number: 292-642-5 | CAS number: 90669-48-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC50 > 1000 mg/L; NOEC = 1000 mg/L (hydrocarbon waxes (petroleum), oxidised), OECD 209, Wadsley (2012)
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
In a GLP compliant study performed according to the standardised guideline OECD 209, the toxicity of the test material to aquatic microorganisms was determined in an activated sludge respiration inhibition test. Activated sludge was exposed to the test material for 3 hours at the following concentrations; 10, 100 and 1000 mg/L, after which the rate of respiration was calculated from the oxygen consumption. Under the conditions of the study the EC50was determined to be in excess of 1000 mg/L. The NOEC was determined to be 1000 mg/L. It was deemed unnecessary to test at concentrations greater than 1000 mg/L.
Since the study was conducted with the read across substance, hydrocarbon waxes (petroleum), oxidised, it has been assigned a reliability score of 2 in line with the criteria of Klimisch (1997). Read across from this substance is justified on the basis of its similar physical and chemical properties to those of the registered substance. Furthermore, it has a very similar chemical structure; the registered substance is an esterified form of the read across substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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