Registration Dossier
Registration Dossier
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EC number: 231-293-5 | CAS number: 7486-38-6
Endpoint summary
Administrative data
Description of key information
Additional information
For disodium adipate no data on biodegradation are available. Therefore, data of the corresponding acid are taken into account for assessment and a read-across approach is applied, based on the following justification.
In aqueous media, disodium adipate and adipic acid acid dissociate
into the corresponding anion (1,6-hexandioic acid ion) and the sodium
ion and hydrogen ion (proton), respectively. Fate, behavior and the
ecotoxicological properties of adipic acid and its disodium salt are
thought to be an effect of the di-carboxylate ion rather than of the
sodium ion or the hydrogen ion (proton), which are normal constituents
in environmental systems and have no relevant ecotoxic properties in low
concentrations.
Therefore a read-across between disodium adipate and adipic acid is
justified.
Biodegradation in water: screening tests
The ready biodegradability of adipic acid was determined in a test conducted according to OECD TG 301 D (Ready biodegradability: Modified OECD Screening Test) showing 83 % degradation after 30 days. This result is supported by a test conducted according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)). After 14 days, more than 90% of adipic acid was degraded.
Based on these results adipic acid is considered to be "Readily Biodegradable".The inherent biodegradability of adipic acid was assessed according to the EU Method C.9 (Biodegradation: Zahn-Wellens Test), showing more than 90% degradation after 5 days.
Biodegradation in water and sediment: simulation tests
In a modified Zahn-Wellens-Test, using surface water from the river Main (Germany), 90% of adipic acid was degraded within 8 days indicating that the substance is biodegradable in surface waters.
A waste water treatment simulation test was performed according to a method which is comparable to the OECD guideline 303 A ("Simulation Test - Aerobic Sewage Treatment. A: Activated Sludge Units). Sludge from a municipal sewage treatment plant was used in this test. After 1 day a DOC removal of 99%was achieved.
Biodegradation in soil
The potential for biodegradation in soil of adipic acid is decribed, by a test conducted according to a national standard method of the U.S. Food and Drug Administration (FDA). An 84 % conversion of adipic acid carbon content to carbon dioxide was found after 30 days aerobic incubation in soil. 60 % degradation was reached in 1 to 6 d. Adipic acid is therefore considered to be readily biodegradable in soil.
In conclusion, based on the presented results, disodium adipate is considered also to be ready biodegradable.
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