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EC number: 235-935-5
CAS number: 13052-09-0
of dermal lesions (following 4-h application) on intact skin
Days after application
Mean score erythema
Mean score oedema
The potential the substance to cause
inflammatory or corrosive changes upon first contact with skin was
assessed by semi-occluded application of 0.5 ml of the test material to
the closely-clipped dorsa of three New Zealand White rabbits for four
hours. Dermal reactions were assessed 1, 24, 48 and 72 hours and six and
nine days after removal of the dressings. Very slight erythema was
observed in all rabbits during the first 24 hours after bandage removal,
continuing in two rabbits up to the 72 hour examination.
Residual dose material adhered to the test
site for up to six days. The test sites of all animals were overtly
normal by Day 9. The test substance is not irritating to skin.
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