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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Not well documented study. Only results are available.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1991

Materials and methods

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
(3aS,3bS,9aS,11aS)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,11H,11aH-cyclopenta[a]phenanthrene-1,7-dione
EC Number:
700-663-2
Cas Number:
1035-69-4
Molecular formula:
C19H24O2
IUPAC Name:
(3aS,3bS,9aS,11aS)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,11H,11aH-cyclopenta[a]phenanthrene-1,7-dione

Test animals

Species:
rat
Sex:
male/female

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
corn oil
Doses:
2000 mg/kg
(Administration volume: 10 ml/Kg)
No. of animals per sex per dose:
5 males
5 females

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Remarks on result:
other: Based on mortality
Mortality:
0/5 per sex

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Acute oral toxicity (LD50) : > 2.000 mg/kg (rats).
According to the 1272/2008 CLP regulation, the substance is not classified for acute oral toxicity