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EC number: 255-288-2 | CAS number: 41272-40-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
MG is very toxic to aquatic life: it's toxic to several species belonging to different trophic levels, like fishes, invertebrates, algae and microorganisms. In general mortality results up to low concentrations; the severity of effects depends on the exposure time and on the species.
Effects observed in fish include effects on skin and on the behaviour similar to those observed in several teleostean species exposure to various pesticides (Srivastava et al. 1993); significant modifications in the activity of LDH's (Lanari et al. 1996). Hepatopancreas, posterior kidney and spleen result the most affected organs during chronic MG exposure (El-Neweshy, 2011). Hematologic effects comprise erythrocyte and leukocyte mean levels decrease (Saglam, 2003; see 6.4).
Furthermore MG result toxic for reproduction because affects the reproductive success and reduces the birth rate (Adeymo, 2011)
MG shows a greater sensitivity at basic pH (pH=9.5) and this is probably due to conversion to cationic form (carbinol)(Bills et al. 1977).The absence of positive charge may facilitate the absorption, whichoccurs almost exclusively through the gills (Plakas et al. 1995; see 6.5).The toxicity of MG is not affected by variation in water hardness (Bills et al. 1993) and by variation of temperature.
Studies on biotransformation and kinetics show that MG is fairly quickly taken up by the fish (within 12 hours), and transformed to Leucomalachite Green (LG), which then is only slowly excreted/degraded from the fish (Kuiper, 2004; see 6.5). MG is characterized by rapid and pH-dependent uptake during waterborne exposure, wide distribution and concentration in the tissues; MG results persistent in tissue (Plakas, 1995; see 6.5).
Schuetze (2008) confirms that LG is the dominating residue in tissue and that the ratio measured for LG and MG varied between 5:1 and 7:1.
The risk for aquatic environmental is very high, so MG should not be used without appropriated risk management measures to avoid any release of the substance directly in aquatic environment or in the municipal waste water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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