Registration Dossier
Registration Dossier
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EC number: 800-777-3 | CAS number: 1351378-24-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErL50(72 h) = 2.3 mg/L (nominal, WAF, OECD 201, Desmodsmus subspicatus)
NOELR(72 h) = 0.36 mg/L (nominal, WAF)
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 2.3 mg/L
- EC10 or NOEC for freshwater algae:
- 0.36 mg/L
Additional information
One study on algal toxicity is available for 2-Butenedioic acid (2Z)-, reaction products with ammonium di-µ3-hydroxyhexacosa-µ-oxododecaoxo¬dodecatungstate(6-) (6:1), ammonium octa-µ-oxodi-µ3-oxo-µ4-oxododecaoxoheptamolybdate(6-) (6:1), nickel(2+) nitrate (1:2) and nickel(2+) sulfate (1:1). This key study was performed according to OECD Guideline 201 using Desmodesmus subspicatus as test organism (Muckle, 2013). As the solubility of the test substance lies below 100 mg/L, a stock solution was prepared by weighing the nominal load of 9.8 mg/L, adding the corresponding amount of dilution water and shaking vigorously for 24 hours. The resulting solution was filtrated through 0.45 µm filters (refering to a water accommodated fraction WAF). Four lower concentrations were prepared by dilution of this solution. Analytical measurements were prepared by determination of Tungsten, Molybdenum and Nickel concentrations at the start and the end of the test period. Based on growth rate inhibition, an ErL50(72 h) of 2.3 mg/L and a NOELR of 0.36 mg/L (nominal, WAF) was derived.
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