Registration Dossier
Registration Dossier
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EC number: 277-242-0 | CAS number: 73037-34-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity test of ditolylether disulfonic acid disodium salt, isomer mixture to fish (Danio rerio) revealed a LC50 of >100 mg/L after 96 hours.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
A study was performed to assess the acute toxicity of ditolylether disulfonic acid disodium salt, isomer mixture to fish (Danio rerio) under static conditions.
The study was conducted in accordance with Council Regulation (EC) No 440/2008, Method C.1 'Acute toxicity for Fish' (2008) which is in most parts equivalent to the OECD Guideline for Testing of Chemicals No. 203 'Fish, Acute Toxicity Test' (1992).
Groups of seven fish of the recommended size were exposed to concentrations of nominally 25, 50 and 100 mg/L of ditolylether disulfonic acid disodium salt, isomer mixture dissolved in dilution water. Auxiliaries used to prepare the test media were an ultrasonic bath and a magnetic stirrer. Observations were made on the numbers of dead fish and the incidence of sublethal effects after 2, 24, 48, 72 and 96 hours of exposure. No mortality was observed up to the highest test concentration of 100 mg/L after 96 hours of exposure, and the result is interpreted as LC50 of >100 mg/L. All results are expressed in terms of nominal concentrations. Effective concentrations ranged from 92.32% to 93.11 % of nominal values at 0 hours and corresponded to 91.87 % of nominal values at 96 hours. This toxicity study is classified as acceptable and satisfies the guideline requirements for the acute Fish study.
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