Registration Dossier
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EC number: 231-600-2 | CAS number: 7647-17-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In this 48-hour semi-static acute toxicity test with Daphnia magna the 48 h EC50 value of cesium chloride was determined as 37.4 mg/L, and the 48 h NOEC was determined to be 23.4 mg/L. The results are based on the nominal test item concentrations.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 37.4 mg/L
Additional information
The purpose of this study was to evaluate the influence of the test item cesium chloride on the mobility respectively survival of Daphnia magna. Young Daphnia were exposed in an immobilisation test to aqueous test media containing the test item for 48 hours at a range of concentration under static conditions.
Based upon the results from the preliminary experiments, nominal concentrations of 9.2; 14.6; 23.4; 37.5 and 60.0 mg/L were investigated in the main study. The test item concentrations remained within ± 20 % of the nominal during the test period of 48 hours; therefore all biological results are based on the nominal concentrations.
The quantification of the test item was performed by a previously validated analytical method. Samples were taken from each testing concentration and the control at the start and at the end of the study and analysed by flame photometer. The measured concentrations of cesium chloride varied between 91 and 114 % of the nominal concentration during the experiment.
The 48-h EC50 value of the test item and their confidence limits were calculated using Probit analysis by SPSS PC+ software. The NOEC, LOEC 24-h EC50 and EC100 were determined directly from the raw data.
In this 48-hour semi-static acute toxicity test with Daphnia magna the 48 h EC50 value was determined as 37.4 mg/L, and the 48 h NOEC was determined to be 23.4 mg/L. The results are based on the nominal test item concentrations.
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