Registration Dossier
Registration Dossier
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EC number: 911-915-8 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The nominal lethal concentration (LC50) of 0.15 mg/L Aminfluorid 297 Olaflur to Poecilia reticulata was calculated as the geometric mean of the highest concentration causing no mortality (0.1 mg/L) and the lowest concentration producing 100 % mortality (0.2 mg/L).
The no-observed-effect concentration (NOEC) was 0.1 mg/L. 100 % mortality (LC100) was seen at the nominal concentration of 0.2 mg/L, reflecting a very steep concentration-effect-curve for Olaflur.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.15 mg/L
Additional information
The acute lethal toxicity (LC50) of Amine fluoride 297 (Olaflur) to Poecilia reticulata (Guppy) was investigated under static conditions over a period of 96 h. 7 fish per concentration were exposed to the test substance. The nominal active ingredient (a.i.) concentration of Aminfluorid 297 Olaflur as selected by a range finding test was 0.1, 0.2, 0.4, 0.8 and 1.6 mg/L, respectively. The individual test concentrations were prepared by dilution of a stock solution. No chemical analysis of test concentrations was conducted.
In the definite test all fish died at the nominal test concentration of 0.4, 0.8 and 1.6 mg/L after 24 h exposure. At 0.2 mg/L all fish had died after 48 h of exposure. No mortality was observed at 0.1 mg/L and in the control after 96 h exposure. Other toxic effects than mortality, e.g. loss of coordination, hypoactivity and swimming on the back, were seen at 0.2 mg/L and higher concentrations. Based on these data it was not possible to calculate the LC values by regression analysis. Therefore, the nominal lethal concentration (LC50) of Aminfluorid 297 Olaflur to Poecilia reticulata was calculated as the geometric mean of the highest concentration causing no mortality (0.1 mg/L) and the lowest concentration producing 100 % mortality (0.2 mg/L) to be 0.15 mg/L. The no-observed-effect concentration (NOEC) was 0.1 mg/L. 100 % mortality (LC100) was seen at the nominal concentration of 0.2 mg/L.
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