Registration Dossier
Registration Dossier
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EC number: 939-621-5 | CAS number: -
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: klimisch criteria
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 977
- Report date:
- 1977
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- Deviations:
- not applicable
- Principles of method if other than guideline:
- no guideline available at that time
24 h application - GLP compliance:
- no
Test material
- Details on test material:
- - Name of test material (as cited in study report): Eutanol G
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- semiocclusive
- Preparation of test site:
- shaved
- Vehicle:
- unchanged (no vehicle)
- Controls:
- not required
- Duration of treatment / exposure:
- 24 h
- Observation period:
- at least 4 days
- Number of animals:
- unknown (4?)
Results and discussion
In vivo
Results
- Irritation parameter:
- other:
- Basis:
- mean
- Time point:
- other: 24 h
- Reversibility:
- fully reversible within: 4 days
- Remarks on result:
- other: slight inflammation
Applicant's summary and conclusion
- Interpretation of results:
- slightly irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Based on the results obtained in this study, the 2-octyldodecan-1-ol is considered to be slightly irritating to the skin.
- Executive summary:
Based on the results obtained in this study, the substance is considered to be slightly irritating.
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