Registration Dossier
Registration Dossier
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EC number: 942-520-9 | CAS number: -
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- hazard unknown (no further information necessary)
Acute/short term exposure
- Hazard assessment conclusion:
- hazard unknown (no further information necessary)
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- hazard unknown (no further information necessary)
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
Workers - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - workers
The substance Guerbet alcohols, C24-26, branched and cyclic has a very low vapour pressure (7.0 E-06 Pa), thus the potential for the generation of inhalable forms is low. Also the use of this substance will not result in aerosols, particles or droplets of an inhalable size. Therefore, exposure to humans via the inhalatory route will be unlikely to occur.
According to experimental data the substance Guerbet alcohols, C24-26, branched and cyclic is practically nontoxic after short-term oral or dermal exposure and a DNEL after short-time exposure must not be derived. A subchronic oral toxicity study showed no evidence of toxicity after oral gavage administration to rats of doses up to 1000 mg/kg bw/d for at least 90 consecutive days. Also the linear alcohol docosan-1 -ol induced no toxicological relevant effects in rats after daily administration of 1000 mg/kg for 26 weeks. Therefore no longterm hazard is expected and no DNEL has to be derived for longterm systemic effects.
As the substance is not irritant to the skin and eyes no local DNELs were derived.
General Population - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- hazard unknown (no further information necessary)
Acute/short term exposure
- Hazard assessment conclusion:
- hazard unknown (no further information necessary)
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- hazard unknown (no further information necessary)
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
General Population - Hazard via oral route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - General Population
The substance Guerbet alcohols, C24-26, branched and cyclic has a very low vapour pressure (7.0 E-06 Pa), thus the potential for the generation of inhalable forms is low. Also the use of this substance will not result in aerosols, particles or droplets of an inhalable size. Therefore, exposure to humans via the inhalatory route will be unlikely to occur.
According to experimental data the substance Guerbet alcohols, C24-26, branched and cyclic is practically nontoxic after short-term oral or dermal exposure and a DNEL after short-time exposure must not be derived. A subchronic oral toxicity study showed no evidence of toxicity after oral gavage administration to rats of doses up to 1000 mg/kg bw/d for at least 90 consecutive days. Also the linear alcohol docosan-1 -ol induced no toxicological relevant effects in rats after daily administration of 1000 mg/kg for 26 weeks. Therefore no longterm hazard is expected and no DNEL has to be derived for longterm systemic effects.
As the substance is not irritant to the skin and eyes no local DNELs were derived.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
