Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 235-120-4 | CAS number: 12070-08-5
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Tissue response to a single intraperitoneal injection of various substances in rats.
- Author:
- SETHI, S., HILSCHER, W., & FLASBECK, R.
- Year:
- 1 973
- Bibliographic source:
- Zbl. Bakt. Hyg. I. Abt. Orig. B., 157: 131-144.
- Reference Type:
- publication
- Title:
- High concentration of injected titanium dioxide in abdominal lymph nodes.
- Author:
- HUGGINS, C.B. & FROEHLICH, J.P.
- Year:
- 1 966
- Bibliographic source:
- J. exp. Med., 124: 1099-1106
- Reference Type:
- publication
- Title:
- Acute oral and parenteral toxicity of four titanate compounds in the rat
- Author:
- BROWN, J.R., MASTROMATTEO, E.
- Year:
- 1 962
- Bibliographic source:
- Ind. Med. Surg., 31: 302-304
- Reference Type:
- publication
- Title:
- Effect of BCG on lymphatic lung clearance of dust with different fibrogenicity. An experimental study on rats.
- Author:
- GOTHE, C.-J., SWENSSON, U.
- Year:
- 1 970
- Bibliographic source:
- Arch. environ. Health, 20: 579-585
- Reference Type:
- publication
- Title:
- Papain-induced emphysema and the elimination of TiO2 particulates from the lungs.
- Author:
- FERIN, J.
- Year:
- 1 971
- Bibliographic source:
- Am. Ind. Hyg. Assoc. J., 32: 157-162
- Reference Type:
- publication
- Title:
- Emphysema in rats and clearance of dust particles.
- Author:
- FERIN, J.
- Year:
- 1 971
- Bibliographic source:
- Inhaled particles and vapours. III. 3rd ed., United Kingdom, Unwin Brothers Ltd. pp. 283-292.
- Reference Type:
- publication
- Title:
- Observations concerning alveolar dust clearance.
- Author:
- FERIN, J.
- Year:
- 1 972
- Bibliographic source:
- Ann. N.Y. Acad. Sci., 200: 66-72
- Reference Type:
- publication
- Title:
- The effects of SO2 on lung clearance of TiO2 particles in rats
- Author:
- FERIN, J. & LEACH, L.J.
- Year:
- 1 973
- Bibliographic source:
- Am. Ind. Hyg. Assoc. J., 34: 260-263
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
