Registration Dossier
Registration Dossier
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EC number: 632-673-7 | CAS number: 26033-20-5
Density
Administrative data
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 Nov 2020 to 15 Jan 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Version / remarks:
- March 04, 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Version / remarks:
- October 2, 2012
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Version / remarks:
- June 2002
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- air comparison pycnometer (for solids)
Test material
- Reference substance name:
- 3-phenyl-1H-pyrazole-4-carbaldehyde
- EC Number:
- 632-673-7
- Cas Number:
- 26033-20-5
- Molecular formula:
- C10H8N2O
- IUPAC Name:
- 3-phenyl-1H-pyrazole-4-carbaldehyde
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Batch (Lot) Number: M19LD3723
- Purity/Composition: 103.6%
- Purity/Composition correction factor: 1.0
- Purity test date : 2020-05-04
- Expiry date: 11 November 2021 (retest date)
- Physical Description: Light yellow powder
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Final preparation of a solid: prior to use in the study, the test material was dried in a desiccator under vacuum using silicagel as the drying agent at 19.5 ± 0.9°C in dark for 96 hours.
Results and discussion
Densityopen allclose all
- Key result
- Type:
- density
- Density:
- 1.35 g/cm³
- Temp.:
- 20 °C
- Type:
- relative density
- Density:
- 1.35
- Temp.:
- 20 °C
Any other information on results incl. tables
The results of the tests on the determination of the density of the test item are given in the table below.
| Test 1 | Test 2 |
Test item mass (g) | 3.6564 | 3.5362 |
Test item volume (cm3) | 2.7173 2.7158 2.7159 2.7208 2.7155 | 2.6221 2.6241 2.6221 2.6220 2.6227 |
Mean test item volume (cm3) | 2.7171 ± 0.0019 | 2.6226 ± 0.0008 |
Density [g/cm3] | 1.346 | 1.348 |
Mean density [g/cm3] | 1.35 | |
The individual measurements were obtained with an accuracy of < 0.02 g/cm3. According to the guideline, the density of the test item is given as the mean value.
Applicant's summary and conclusion
- Conclusions:
- A gas comparison stereopycnometer was used for the determination of the density and relative density of JNJ-39125190-AAA (T003897).
The density of the test item at 20ºC was 1.35 g/cm3 (1.35E3 kg/m3).
The relative density was 1.35.
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