Registration Dossier
Registration Dossier
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EC number: 853-587-8 | CAS number: 199387-97-8
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2022-01-17 to 2022-05-18
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: Preliminary test
- Key result
- Water solubility:
- < 9 mg/L
- Conc. based on:
- test mat. (dissolved fraction)
- Temp.:
- 23 °C
- pH:
- 4.4
- Remarks on result:
- other: In the preliminary test the water solubility of the test item at room temperature was estimated to be > 9 mg/L
- Conclusions:
- The water solubility of the test item is < 9 mg/L
- Executive summary:
According to the preliminary test described in OECD Test Guideline 105 and EU Method A.6., the water solubility of the test item at room temperature was estimated to be < 9 mg/L.
Reference
The observations of the preliminary test are summarized in Table 1.
Table 1: Results for the water solubility at 23 °C
Amount of test item [mg] | Total volume of added water [mL] | Stirring time [h:min] | Remark |
100 | 0.1 | -- | not dissolved |
0.6 | -- | not dissolved | |
1.6 | 0:031 | not dissolved | |
3.6 | 0:031 | not dissolved | |
13.6 | 0:031 | not dissolved | |
100 | 0:061 | not dissolved | |
7.24 | 100 | 141:30 | not dissolved |
4.70 | 250 | 141:30 | not dissolved |
4.53 | 500 | 141:30 | not dissolved |
1 The mixtures were treated in an ultrasonic bath
The solubility of the test item at room temperature was estimated to be < 9 mg/L (pH = 4.4)
Description of key information
According to the preliminary test described in OECD Test Guideline 105 and EU Method A.6., the water solubility of the test item at room temperature was estimated to be < 9 mg/L.
Key value for chemical safety assessment
Additional information
Estimated value < 9 mg/L
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